The dodo’s genome has been sequenced from a DNA sample, but that’s just the first hurdle to overcome in bringing a species back from the dead

By Paul McGuinness

Published: Sunday, 02 April 2023 at 12:00 am


Endemic to the small island of Mauritius, east of Madagascar in the Indian Ocean, the dodo was a large, flightless bird that went extinct some time in the 17th century following the arrival of European settlers in the previous century. But what exactly caused the dodo to go extinct? And could it ever be brought back to life?

Why did the dodo go extinct?

When Europeans began to settle on Mauritius in the 16th century, the sailors and the invasive species they brought with them sealed the dodo’s fate. Before they arrived, the dodo lived a charmed life on an island where food was plentiful and predators absent. But the sailors and their animals hunted it for food, raided its nests for eggs, and destroyed its habitat.

Its brutal eradication from its only home has seen the dodo become almost a byword for extinction. But with the advance of genetic engineering technologies, would it be possible one day to bring the dodo back from extinction?

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Dodo and guinea pig, 1750, from A Natural History of Uncommon Birds by George Edwards. © Ann Ronan Pictures/Print Collector/Getty

Can the dodo be brought back from extinction?

In 2022, Beth Shapiro from the Genomics Institute at the University of California, Santa Cruz, announced the sequencing of the dodo’s genome. It was sequenced from a DNA sample taken from a specimen held at Copenhagen’s Natural History Museum. So is this icon of extinction poised to return from the dead?

“There are a tonne of existing technical challenges that would need to be solved in order to bring a dodo back to life,” she told us.

“First, one needs to be able to figure out what genetic differences in the dodo genome make the dodo look and act like a dodo. One would also need to figure out how to make those genetic changes, which are surely more than a few, in the types of cells that are destined to become a living animal. In birds, this would mean using gene-editing tools on what are known as ‘primordial germ cells’, which are the cells that will eventually become sperm or eggs. After that, one would have to solve all of the normal problems associated with captive breeding and husbandry of a species that no longer exists.”

Would the dodo survive today?

Even if it were possible to recreate the dodo, that wouldn’t solve the problems that caused the bird to go extinct in the first place, as Beth explains: “We believe that dodos became extinct because introduced species including rats, cats and pigs consumed their eggs. Because dodos didn’t fly, they nested on the ground.

“This made their nests easy access for potential predators and consumers of eggs. It would not make sense to bring dodos back to Mauritius unless this challenge could be solved.”

It’s a hot topic, with strong views on all sides. “De-extinction is not a solution to the extinction crisis of the present day,” Beth says.

Rather, such technologies offer the potential to edit the genomes of current threatened species in order to help them adapt to changes in habitat and climate.

“Our new biotechnologies may someday make it possible to transfer some extinct traits to living species, but the end products of any project like this will be something different than the species that once existed. Every organism is more than just the As, Ts, Cs, and Gs that make up their DNA code. We are combined products of our DNA and the environment in which we live.”

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The dodo’s home island of Mauritius is a tropical paradise in the Indian Ocean. © ThomasFluegge/Getty

So does this rule out the idea of bringing the dodo back from the dead?

“We may get close someday. We may figure out how to make enough changes in a genome that we can engineer something that is physically similar to a dodo. And maybe that bird, returned to the Mauritian ecosystem, will fill the ecological niche that the dodo once filled and provide some improved stability to the Mauritian ecosystem. And that would be great.”

So why sequence the DNA?

Beth believes there’s a more pressing concern that this kind of work may be able to help with. “These technologies will also help us to solve more proximate challenges. We will learn to edit the genomes of species that are still alive but in danger of becoming extinct, to help them to adapt to their rapidly changing habitats.

“The same technologies that might eventually be used to re-create something that approximates an extinct species will be useful to help preserve species that are still alive. To protect those species from going the way of the dodo.”

Main image: The skeleton of a dodo is displayed beside a reconstruction of the flightless bird, 1938. © Hulton-Deutsch Collection/Getty